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Sam Worthington

as Jake Sully

Zoe Saldaña

as Neytiri

Stephen Lang

as Colonel Miles Quaritch

Sigourney Weaver

as Kiri

Oona Chaplin

as Varang

Giovanni Ribisi

as Parker Selfridge

Joel David Moore

as Norm Spellman

CCH Pounder

as Mo'at

Matt Gerald

as Corporal Lyle Wainfleet

Jemaine Clement

as Dr. Ian Garvin

Michelle Yeoh

as Dr. Karina Mogue

Cliff Curtis

as Tonowari

Keston John

Dileep Rao

as Dr. Max Patel

Filip Geljo

as Aonung

Britain Dalton

as Lo'ak

Jack Champion

as Miles 'Spider' Socorro

Duane Evans Jr.

as Rotxo

Trinity Jo-Li Bliss

as Tuktirey 'Tuk'

Bailey Bass

as Tsireya